LSU
CAMD

 

Challa Kumar, Ph.D.

Title:  Director, Nanofabrication & Nanomaterials
Center for Advanced
Microstructures and Devices
6980 Jefferson Hwy.
Baton Rouge, LA 70806
Office Tel. : (225) 578-9320
Fax: (225) 578-6954

Academic Preparation:

Ph.D (Chemistry)

Honors and Awards

  • Member, NIH Review Panel, Cancer Diagnostic and Therapeutic Agents Enabled by Nanotechnology, July 28-30, 2011.
  • Member, NIH Review panel -SBIR Proposals, March 03, 2011.
  • Editor-in-Chief, Nanotechnology Reviews, 2011 onwards
  • Invited Speaker, Advanced Light Source, Berkeley, User Workshop, 14th October 2010.
  • Invited Speaker, Nanomedicine Symposium, Universitätsklinik Erlangen, Germany, September 3-5th 2010.
  • NIH Review Panel on Nanotechnology Platforms for Cancer, March 30, 2010.
  • Invited speaker, First Unither Nanomedical & Telemedical Technology Conference., Orford, Quebec, Canada, April, 2008.
  • President & CEO, Magnano Technologies
  • Invited speaker at Seeing is Believing: The Future of Molecular and Biomolecular Imaging, March 11 - 13, 2007, Duke University.
  • Invited to NSF panel on Nanomanufacturing, Feb 20th, 2007.
  • Member, Scientific Advisory Board, Life Boat Foundation
  • Member, Scientific Advisory Board, Maximum Life Foundation
  • Invited to National Academy of Sciences meeting (Keck Futures Initiative conference), November 9-11, 2006.
  • Invited to be on DFG (Deutsche Forschungsgemeinschaft), German Research Foundation, Review Panel, November 3rd 2006
  • Winner of Nano 50 Awards, 2006.
  • Series Editor- A ten volume series on ‘Nanotechnologies for Life Sciences’ being published by Wiley-VCH.
  • Runner-up, CEO of the Team participated in a Business Plan competition conducted by Louisiana Business Technology Council, 2006.
  • Program Chair, CAMD Summer workshop on “ Nanotechnology in biology, Biotechnology and Medicine,” 2004.
  • Member, Scientific Advisory Board, Maximum Life Foundation
  • Nano 50 Technology Award, 2006.
  • Program Chair, CAMD Summer workshop on “ Nanotechnology in biology, Biotechnology and Medicine,” 2004.
  • Chairman, Session on Magnetic nanoparticles for Therapy, Nanomaterials, Business Commun., 2004.
  • Editor-in-Chief, Journal of Biomedical Nanotechnology, 2004-2005
  • Author, Strategy Document for Research and Development for ICI India Ltd, 1997.
  • Referee for international scientific journals: Journal of the American Chemical Society, Angewandte Chemie, Chemistry of Materials, Journal of Biomedical Nanotechnology, Journal of Nanoscience and Nanotechnology.

Professional Media Features

Publications - Refereed Journals

  1. Losovyj Ya.; Li, S-C.; Lozova, N.; Katsiev, K.;  Stellwagen, D.;  Diebold, U.; Kong, L.;  and Kumar, C.S.S.R.;  Evidence for s–d Hybridization in Au38 Clusters, J.Phys.Chem.C., 2012 (accepted)
  2. Li, S.; Roy, A.; Lichtenberg, H.; Merchan, G.; Kumar, C.S.S.R.;  and  Köhler, J.M.; Local Structure of ZnO Micro Flowers and Nanoparticles Obtained by Micro Segmented Flow Synthesis, ChemPhysChem, 2012 (accepted)
  3. S. Biswas, J. T. Miller, Y. Li, K. Nandakumar, and C. S.S.R. Kumar, Developing Millifluidic Platform for Synthesis of Ultra-small Nanoclusters (UNCs): Ultra-small Copper Nanoclusters (UCNCs) as a Case Study, Small, 2012 ( Accepted).
  4. D. Stellwagen, A. Weber, L.S. Bovenkamp, R. Jin, H. Bitter, C.S.S.R. Kumar, Ligand control in thiol stabilized Au38 clusters, RSC Adv., DOI: 10.1039/C2RA00747A, 2012 (accepted).
  5. N. D. Subramanian, C. S.S.R. Kumar, K. Watanabe, P. Fischer, R. Tanaka and J. J. Spivey, A DRIFTS study of CO adsorption and hydrogenation on Cu-based core-shell nanoparticles, Catalysis Science & Technology, 2012 (Accepted).
  6. S. Gaur, J. T. Miller, D. Stellwagen, A. Sanampudi, C. S.S.R. Kumar, and J. J. Spivey, Synthesis, characterization, and testing of supported Au catalysts prepared from atomically-tailored Au38(SC12H25)24 clusters, Phys. Chem. Chem. Phys., 2012, 14, 1627-1634.
  7. Y. Li, A. Sanampudi, V. R. Reddy, S. Biswas, K. Nandakumar, D. Yamane, J. Goettert, and C.S.S.R. Kumar, Size Evolution of Gold Nanoparticles in a Millifluidic Reactor, ChemPhysChem, 2012, 13 (1),177–182.
  8. Nachal D. Subramanian, Juana Moreno, James J. Spivey and Challa S.S.R. Kumar,  Copper Core-Porous Manganese Oxide Shell Nanoparticles, J.Phy.Chem.C., 2011, 115(30), 14500-14506.
  9. Roy, Amitava; Morikawa, Eizi; Bellamy, Henry; Kumar, Challa; Goettert, Jost; Suller, Victor; Morris, Kevin; Kurtz, Richard; Scott, John Status of the Center for Advanced Microstructures and Devices (CAMD)-2010, Nuclear Instruments & Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors, and Associated Equipment (2011), 649(1), 15-18.
  10. Challa S.S.R.Kumar and Faruq Mohammad, Magnetic Nanomaterials for Hyperthermia-based Therapy and Controlled Drug Delivery, Adv. Drug Del. Rev., 2011 63, 789-808.
  11. Challa S.S.R.Kumar and Faruq Mohammad, Magnetic Gold Nanoshells: Step-wise Changing of Magnetism through Step-wise Biofunctionalization, J. Phys. Chem.Lett., 2010, 1(200), 3141–3146.
  12. Faruq Mohammad, Gopalan Balaji, Andrew Weber, Rao M. Uppu, and Challa S. S. R. Kumar, Influence of Gold Nanoshell on Hyperthermia of Super Paramagnetic Iron Oxide Nanoparticles (SPIONs), J. Phys. Chem. C, 2010, 114 (45), 19194–19201.
  13. Jason Jordan, Challa S.S.R.Kumar and Chandra S. Theegala, Preparation And Characterization Of Cellulase-Bound Magnetite Nanoparticles (SPION),  Journal of Molecular Catalysis B: Enzymatic, 2011, 68(2), 139-146
  14. Challa S.S.R. Kumar, Nanotechnology Tools in Pharmaceutical R&D, Materials Today, 12, 24-30, 2010.
  15. Branca T, Cleveland ZI, Leuschner C, Kumar C, Fubara B, Maronpot RR, Warren W, Driehuys B. Hyperpolarized 3He MRI to Detect Lung Metastases Targeted by Magnetic Nanoparticles. Proc. Natl. Acad. Sci. 107:3693-3697, 2010.
  16. G. Balaji, Rohini, De Silva, V. Palshin, N. Desilva, G. Palmer, and Challa S. S. R. Kumar, Reaction Pathway Towards Formation of Cobalt Single Chain Magnets and Nanoparticles, Materials Science and Engineering: B, 167(2), 107-113, 2010.
  17. Challa S.S.R. Kumar, Nanotechnology Tools in Pharmaceutical R&D, Materials Today, 12, 24-30, 2010.
  18. G. Balaji, G. L. Bovenkamp, V. Palshin and C. S.S.R. Kumar, Single Molecular Magnet - Gold Nanoparticle Composites, 2009 MRS Fall Symposium Proceedings, Accepted.
  19. Branca T, Cleveland ZI, Leuschner C, Kumar C, Fubara B, Maronpot RR, Warren W, Driehuys B. Hyperpolarized 3He MRI to Detect Lung Metastases Targeted by Magnetic Nanoparticles. Proc. Natl. Acad. Sci. 107:3693-3697, 2010.
  20. G. Balaji, Rohini, De Silva, V. Palshin, N. Desilva, G. Palmer, and Challa S. S. R. Kumar, Reaction Pathway Towards Formation of Cobalt Single Chain Magnets and Nanoparticles, Materials Science and Engineering: B, 167(2), 107-113, 2010.
  21. Nachal Devi Subramanian, Balaji Gopalan, Challa S.S.R. Kumar and James J. Spivey, Development of cobalt - copper nanoparticles as catalysts for higher alcohol synthesis from syngas, Catalysis Today (2009), 147(2), 100-106.
  22. Rosa T. Branca, Yuming M. Chen, Vladimir Mouraviev, Gigi Galiana, Elizabeth R. Jenista, Challa Kumar, Carola Leuschner, and Warren S. Warren, iDQC Anisotropy Map Imaging for Tumor Tissue Characterization In Vivo, Magnetic Resonance in Medicine 61:937–943 (2009).
  23. Meng J, Fan J, Galiana G, et al LHRH-functionalized superparamagnetic iron oxide nanoparticles for breast cancer targeting and contrast enhancement in MRI. Materials Science and Engineering: C, (2009), 29(4), 1467-1479.
  24. Yujun Song, Josef Hormes and Challa S.S.R. Kumar, Microfluidic Synthesis of Nanomaterials, Small, 4(6), 698-711, 2008.
  25. Michelle C. Urbina, Svetlana Zinoveva, Toby Miller, Cristina M. Sabliov, William T. Monroe, and Challa S. S. R. Kumar., Investigation of Magnetic Nanoparticle-Polymer Composites for Multiple-controlled Drug Delivery, J. Phys.Chem. C., 112(30), 11102-11108, 2008.
  26. De Silva, Rohini M.; Palshin, Vadim; Nalin de Silva, K. M.; Henry, Laurence L.; Kumar, Challa S. S. R.. A new role for surfactants in the formation of cobalt nanoparticles. Journal of Materials Chemistry (2008), 18(7), 738-747.
  27. Zinoveva, Svetlana; De Silva, Rohini; Louis, Russell D.; Datta, Proyag; Kumar, Challa S. S. R.; Goettert, Jost; Hormes, Josef. The wet chemical synthesis of Co nanoparticles in a microreactor system: A time-resolved investigation by X-ray absorption spectroscopy. Nuclear Instruments & Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors, and Associated Equipment (2007), 582(1), 239-241.
  28. Roy, Amitava; Morikawa, Eizi; Bellamy, Henry; Kumar, Challa; Goettert, Jost; Suller, Victor; Morris, Kevin; Ederer, David; Scott, John. Status of the Center for Advanced Microstructures and Devices (CAMD)-2007. Nuclear Instruments & Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors, and Associated Equipment (2007), 582(1), 22-25
  29. Kumar, Challa S. S. R.; Leuschner, Carola; Urbina, Michelle; Ozkaya, Tevhida; Hormes, Josef. Glutaric acid as a spacer facilitates improved intracellular uptake of LHRN-SPION into human breast cancer cells. International Journal of Nanomedicine (2007), 2(2), 175-179.
  30. De Silva, Rohini M.; Palshin, Vadim; Fronczek, Frank R.; Hormes, Josef; Kumar, Challa S. S. R..   Investigation of the Influence of Organometallic Precursors on the Formation of Cobalt Nanoparticles.    Journal of Physical Chemistry C  (2007),  111(28),  10320-10328.
  31. Astete, Carlos E.; Kumar, Challa S. S. R.; Sabliov, Cristina M.   Size control of poly(D,L-lactide-co-glycolide) and poly(D,L-lactide-co-glycolide)-magnetite nanoparticles synthesized by emulsion evaporation technique.    Colloids and Surfaces, A: Physicochemical and Engineering Aspects  (2007),  299(1-3),  209-216.
  32. Kizilkaya, Orhan; Ono, Masaki; Bianchetti, Chris; Kumar, Challa S. S. R.; Morikawa, Eizi.   Ultrathin film assembly of sulfobetaine-stabilized palladium nanoparticles investigated by photoemission spectroscopy.    Materials Letters  (2007),  61(7),  1533-1536.
  33. Yujun Song,  Hartwig Modrow,  Laurence L. Henry,  Cheng K. Saw,  Ed E. Doomes, Vadim Palshin,  Josef Hormes  and Challa S S R Kumar, Microfluidic Synthesis of Cobalt Nanoparticles, Chem. Mater., 18 (12), 2817 -2827, 2006.
  34. Carola Leuschner, Challa SSR Kumar, Zhou, Jikou, Soboyejo, Winston O, William Hansel, and Josef Hormes, LHRH-conjugated magnetic iron oxide nanoparticles for detection of breast cancer metastases, Breast Cancer Research and Treatment ( 2006 ), 99(2),  163-176.
  35. Zhou, J.; Leuschner, C.; Kumar, C.; Hormes, J.; Soboyejo, W. O.   A TEM study of functionalized magnetic nanoparticles targeting breast cancer cells.    Materials Science & Engineering, C: Biomimetic and Supramolecular Systems  (2006),  26(8),  1451-1455.
  36. Bala G. Nidumolu, Michelle C. Urbina, Josef Hormes, Challa S. S. R. Kumar, and W. Todd Monroe, Functionalization of Gold and Glass Surfaces with Magnetic Nanoparticles Using Biomolecular Interactions, Biotechnology Progress, 22(1), 91-95, (2006).
  37. Zhou, Jikou; Leuschner, Carola; Kumar, Challa; Hormes, Josef F.; Soboyejo, Winston O., Sub-cellular accumulation of magnetic nanoparticles in breast tumors and metastases.,  Biomaterials  (2006),  27(9),  2001-2008.
  38. Lu, Zonghuan; Prouty, Malcolm D.; Guo, Zhanhu; Kumar, Challa S. S. R.; Lvov, Yuri M..  Layer-by-layer nanoengineered magnetic encapsulation system for drug delivery.    PMSE Preprints (2005), 93, 656-657.
  39. J. Zhou, C. Leuschner, C. Kumar, J. Hormes and W.O. Soboyejo, A TEM study of functionalized magnetic nanoparticles targeting breast cancer cells, Mater.Sci.Eng C, In Press, Corrected Proof, Available online 27 September 2005.
  40. Carola Leuschner, Challa SSR Kumar, William Hansel, and Josef Hormes, Targeting breast cancer cells and their metastases through luteinizing hormone releasing hormone (LHRH) receptors using magnetic nanoparticles, J.Biomed.Nanotech., 1(2), 229-233, 2005.
  41. Yujun Song, E. E. Doomes, John Prindle, Roland Tittsworth, Josef Hormes and Challa SSR Kumar Investigations into Sulfobetaine-stabilized Cu Nanoparticle Formation:Towards Development of a Micro fluidic Synthesis, J.Phys.Chem.B 109(19); 9330-9338, 2005.
  42.  C. Milburn,J. Zhou, O. Bravo, C. Kumar, and W. O. Soboyejo, Sensing Interactions Between Vimentin Antibodies and Antigens for Early Cancer Detection, J.Biomed.Nanotech. 1(1), 30-38, 2005.
  43. Kumar, Challa S. S. R..  Welcome to the Journal of Biomedical Nanotechnology.    Journal of Biomedical Nanotechnology  (2005),  1(1),  1-2.
  44. H. Modrow, N. Palina, C.S.S.R. Kumar, E.E. Doomes, M. Aghasyan, V.Palshin, R. Tittsworth, J.C. Jiang, J. Hormes, Characterization of size-dependent structural and electronic properties of CTAB-stabilized cobalt nanoparticles by X-ray absorption spectroscopy, Physica Scripta, T115, 790-793, 2005.
  45. Zonghuan Lu, Malcolm D. Prouty, Zhanhu Gao, Vladimir O. Golub, Challa S.S.R. Kumar, Yuri M.  Lvov, Magnetic Switch of Permeability for Polyelectrolyte Microcapsules Embedded with Co@Au Nanoparticles,   Langmuir, 21(5), 2042 -2050, 2005.
  46. J. Hormes, H. Modrow, H. Bonnemann and Challa S.S.R. Kumar, Electronic, magnetic and geometric properties of functionalized magnetic nanoparticles, J. Appl. Phys. Lett (2005),  97(10),  10R102-10R102-6.
  47. Guo, Zhanhu; Kumar, Challa S. S. R.; Henry, Laurence L.; Doomes, E. E.; Hormes, Josef; Podlaha, Elizabeth J.  Displacement Synthesis of Cu Shells Surrounding Co Nanoparticles.    Journal of the Electrochemical Society  (2005),  152(1),  D1-D5
  48. Challa S.S.R.Kumar, Carola Leuschner, E. E. Doomes, Larry Henry, Martha Juban, and Josef Hormes, Efficacy of lytic peptide bound magnetite nanoparticles in destroying breast cancer cells, Journal of Nanoscience and Nanotechnology, 4 (3), 245-249, 2004.
  49. Y. Song, Challa S.S.R.Kumar, and Josef Hormes, Fabrication of a SU-8 based microfluidic reactor on a  PEEK substrate sealed by a Flexible semi-solid transfer’ (FST) process, Journal of Micromachining and  Microengineering, 14, 1-9, 2004.
  50. Y. Song, Challa S.S.R.Kumar, and Josef Hormes, Synthesis of Pd nanoparticles using a continuous flow polymeric micro reactor, Journal of Nanoscience and nanotechnology, 4(7), 788-793, 2004.
  51. Ch.S.S.R.Kumar, M.Aghasyan, H. Modrow, J. Hormes, and R. Tittsworth , Gold nanoparticles in polymer  micro beads -one pot synthesis and XANES characterization, Journal of Metastable & Nanocrystalline  Materials, 23, 343-347, 2004.
  52. Challa S.S.R.Kumar, Mher Aghasyan, Hartwig Modrow, Edward Doomes, Cindy Henk ,Josef Hormes and Rolland Tittsworth, Synthesis and Characterization of S-Au Interaction in Gold Nanoparticle bound Polymeric Beads, Journal of Nanoparticle Research, 6, 369-376, 2004
  53. G. Wiche, J. Gottert, Y.Song, J.Hormes and Ch.S.S.R.Kumar, Functional micro devices using 'nanoparticle-photo resist' composites, Int. J. Comp. Eng. Sci., 4(3), 525-528, (2003).
  54. Kumar, Challa S. S. R.; Modrow, Hartwig; Hormes, Josef. Characterisation of sonochemically produced PdO nanoparticles by X-ray absorption near edge structure spectroscopy, Particle & Particle Systems Characterization (2002), 19(5), 336-341.
  55. E. Morikawa, J.D.Scott, J. Goettert, G. Aigeldinger, C.S.S.R. Kumar, B.C. Craft, P.T.   Sprunger, R.C. Tittsworth, and F.J.Hormes, “Status  of the Centre for Advanced Microstructures and Devices 2001”, Review of Scientific Instruments, 73,3, 2002.
  56. Kumar, Ch S. S. R.; Nijasure, Avinash M. “Vulcanization of rubber: how to alter molecular structure and influence physical properties”, Resonance, (1997), 2(4), 55-59.
  57. Ch.S.S.R.Kumar, S.Malladi and S.Yakkundi, “Limonoids from the seeds of azadirachta Indica”, Phytochemistry, 43, 2, 451-455, 1996.
  58. Krishnaswamy, N. R.; Kumar, Ch Siva Sai Ramana. “Absorption, emission and mass spectral characteristics of oligothiophenes and their derivatives”. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry (1993), 32B(7), 766-71.
  59. Krishnaswamy, N. R.; Kumar, C. Siva Sai Ramana. “Synthesis of 2,5-dipropyl (ii)cycloheptanol via dimethyldithienotropone” Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry (1992), 31B(7), 449-51.
  60. Krishnaswamy, N. R.; Kumar, C. Siva Sai Ramana, Prasanna, “ Photochemical reactions of thienyl-, bithienyl-, and terthienyl methanols”, Journal of Chemical Research (S), 166, 1991; J.Chem.Res. (M), 1801-1830, 1991.

Publications - Books and Book Chapters

  1. A ten volume book series on “Nanomaterials for Life Sciences” published by Wiley-VCH 2008-2011, Editor : Challa S.S.R.Kumar. Go to website
  2. A two volume book series on “Microfluidic Devices in Nanotechnology” published by Wiley 2010, Editor : Challa S.S.R.Kumar. Go to website
  3. Challa S.S.R.Kumar, Nanomaterials for Medical Applications, KirkOthmer Encyclopedia of Chemical Engineering, John Wiley & Sons, Inc., 2007.
  4. “Nanofabrication towards biomedical applications”, Editors : Challa S.S.R.Kumar, Josef Hormes and Carola Leuschner, by Wiley-VCH 2005
  5. Carola Leuschner and Challa S.S.R.Kumar, “Nanotechnology in Cancer therapy”, a book chapter in Nanofabrication towards biomedical applications, Editors: Challa S.S.R.Kumar, Josef Hormes and Carola Leuschner, by Wiley-VCH 2005.
  6. A ten volume book series on “ Nanotechnologies for Life Sciences” being published by Wiley-VCH 2005-2006, Editor : Challa S.S.R.Kumar. Go to website

Patents

  1. Kumar, Challa S. S. R.; De Silva, Rohini M.; Hormes, Josef. Method for making cobalt nanomaterials. PCT Int. Appl. (2008), 24pp. CODEN: PIXXD2 WO 2008034062 A2 20080320 AN 2008:353358.
  2. Leuschner, Carola; Lvov, Yuri M.; Kumar, Challa S. S. R.. Layered nanoparticles for self-aggregation prevention and sustained release of small molecule drugs such as ligand-lytic peptide conjugates for cancer targeting. PCT Int. Appl. (2007), 47pp. CODEN: PIXXD2 WO 2007115033
  3. Leuschner, Carola; Kumar, Challa S. S. R.; Hansel, William; Hormes, Josef.   In vivo imaging and therapy with magnetic nanoparticle conjugates.    PCT Int. Appl.  (2007),     79pp.  WO  2007021621.
  4. Kumar, Challa; Podlaha, Elizabeth J.; Guo, Zhanhu; Hormes, Josef.   Core-shell nanostructures and microstructures.    U.S. Pat. Appl. Publ.  (2006),     24pp.  US  2006177660.
  5. Song, Yujun; Kumar, Challa; Hormes, Josef.   Fabrication of a completely polymeric microfluidic reactor for chemical synthesis.    U.S. Pat. Appl. Publ.  (2006),     19 pp.  US  2006014271.
  6. Singh, Anil Kumar; Kumar, Challa Siva Sai Raman; Achar, Sudhir.   Process for the preparation of polymers from vinylic monomers using tetraethylthiuram monosulfide as photoinitiator.    Indian Pat. Appl.  (2005),     13pp.  IN  2000MU00638.
  7. Kumar, Challa Siva Sai Ramana; Salunkhe, Ranjan Vaman.   A process for the preparation of acetonyl N,N-diethyldithiocarbamate via the UV irradiation of tetraethylthiuram monosulfide in acetone.    Indian  (1999),     11 pp.  IN  182660.
  8. Ravindranath, Bhagavathula; Thejavathi, Renukappa; Kumar, Challa Siva Sai Ramana; Yakkundi, Shirish Ranganath.   Chromatographic method and its use for separation of azadirachtin.    Can. Pat. Appl.  (1997),     26 pp.  CA  2184564.